Transporter Screen

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Transporters and channels control the uptake and efflux of essential nutrients, ions, cellular waste and drugs into and out of cells and organelles. Transporters mediate drug disposition and are major determinants of the pharmacokinetic, safety and efficacy profiles of drugs. Recent studies have shown that the inhibition or activation of a specific transporter that involves in the absorption, disposition, metabolism, elimination and toxicity of a drug could have significant clinical effects ranging from lowering drug efficacy to compromising safety etc. 

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